Feeds

Baldness fix from foreskin follicles

Keep the tip

  • alert
  • submit to reddit

Choosing a cloud hosting partner with confidence

Boffins from America and the UK are claiming success in the decades-long hunt to create new hair follicles: they've successfully grown follicles in the lab, on circumcised foreskins.

The Columbia University / Durham University group of biologists, geneticists and dermatologists took cells from newborns' foreskins, and grew them in a 3D culture, which they found allowed the cells to create new hair follicles.

As they explain in the abstract of a paper published at PNAS, the rapid transition of dermal papilla cells to a two-dimensional environment causes “early loss of their hair-inducing capacity”.

The researchers note that this kind of growth has long been observed in rodents, but never before in human cells: “rodent hair follicle-derived dermal cells can interact with local epithelia and induce de novo hair follicles in a variety of hairless recipient skin sites. However, multiple attempts to recapitulate this process in humans using human dermal papilla cells in human skin have failed, suggesting that human dermal papilla cells lose key inductive properties upon culture.”

The hair-inducing capacity, they write, can be at least partially restored by culturing altered cells in the 3D structure: “we show that human dermal papilla cells, when grown as spheroids, are capable of inducing de novo hair follicles in human skin”.

According to the Sydney Morning Herald, the cultures were grafted onto the backs of mice. Within six weeks, five out of the seven donor samples produced follicles. ®

Choosing a cloud hosting partner with confidence

More from The Register

next story
Holy vintage vehicles! Earliest known official Batmobile goes on sale
Riddle me this: are you prepared to pay US$180k?
Bible THUMP: Good Book beats Darwin to most influential tome title
Folio Society crowns fittest of surviving volumes
'Open source just means big companies can steal your code.' O RLY?
Plus: Flame of the Week returns, for one night only!
U wot? Silicon Roundabout set to become Silicon U-BEND
Crap-spouting London upstarts to get permanent road closure
Hey, you, PHONE-FACE! Kickstarter in-car mobe mount will EMBED your phone into your MUG
Stick it on the steering wheel and wait for the airbag to fire
NEWSFLASH: It's time to ditch dullard Facebook chums
Everything hot in tech, courtesy of avian anchor Regina Eggbert
'It is comforting to know where your data centres are.' UK.GOV does NOT
Plus: Anons are 'wannabes', KKK says, before being pwned
Criticism of Uber's journo-Data Analytics plan is an Attack on DIGITAL FREEDOM
First they came for Emil – and I'm damn well SPEAKING OUT
prev story

Whitepapers

Choosing cloud Backup services
Demystify how you can address your data protection needs in your small- to medium-sized business and select the best online backup service to meet your needs.
Forging a new future with identity relationship management
Learn about ForgeRock's next generation IRM platform and how it is designed to empower CEOS's and enterprises to engage with consumers.
Reg Reader Research: SaaS based Email and Office Productivity Tools
Read this Reg reader report which provides advice and guidance for SMBs towards the use of SaaS based email and Office productivity tools.
The hidden costs of self-signed SSL certificates
Exploring the true TCO for self-signed SSL certificates, including a side-by-side comparison of a self-signed architecture versus working with a third-party SSL vendor.
Top 5 reasons to deploy VMware with Tegile
Data demand and the rise of virtualization is challenging IT teams to deliver storage performance, scalability and capacity that can keep up, while maximizing efficiency.