Feeds

HIV vaccine safe for Phase II human trials

Canadian university claim no adverse effects from first tests

Secure remote control for conventional and virtual desktops

Researchers from the Schulich School of Medicine & Dentistry at Canada's University of Western Ontario have issued a statement saying the first phase of clinical trials of an HIV vaccine have produced “no adverse effects observed including local reactions, signs/symptoms and laboratory toxicities”.

The Reg understands the trial of the vaccine, dubbed'SAV001-H' involved only 40 patients, all of which were HIV-positive. Some of those participating in the trial received a placebo.

The researchers say data from the trial is still being analysed, but say the results they have been able to gather show “significant increase in the HIV-1 antibody formations after SAV001-H administration compared to the base line in some patients.”

That result, along with the lack of adverse effects, sees the researchers declare “we are now prepared to take the next steps towards Phase II and Phase III clinical trials” among a wider population.

The vaccine is described as a a “killed whole virus”, a type of vaccine that uses a genetically-engineered version of the HIV virus that is subjected to chemicals and radiation in ways that allow it to fight HIV without hurting the patient. Such vaccines are already used to treat polio, rabies, influenza and other diseases.

There's still a long way to go before SAV001-H becomes widely available. As the USA's national Institutes of Health explains, Phase II trials use a larger sample to test whether a drug “is effective and to further evaluate its safety” while Phase III trials work with more people again to test “effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.” ®

Secure remote control for conventional and virtual desktops

More from The Register

next story
Boffins say they've got Lithium batteries the wrong way around
Surprises at the nano-scale mean our ideas about how they charge could be all wrong
Thought that last dinosaur was BIG? This one's bloody ENORMOUS
Weighed several adult elephants, contend boffins
Europe prepares to INVADE comet: Rosetta landing site chosen
No word yet on whether backup site is labelled 'K'
India's MOM Mars mission makes final course correction
Mangalyaan probe will feel the burn of orbital insertion on September 24th
City hidden beneath England's Stonehenge had HUMAN ABATTOIR. And a pub
Boozed-up ancients drank beer before tearing corpses apart
'Duck face' selfie in SPAAAACE: Rosetta's snap with bird comet
Probe prepares to make first landing on fast-moving rock
Archaeologists and robots on hunt for more Antikythera pieces
How much of the world's oldest computer can they find?
prev story

Whitepapers

Providing a secure and efficient Helpdesk
A single remote control platform for user support is be key to providing an efficient helpdesk. Retain full control over the way in which screen and keystroke data is transmitted.
Saudi Petroleum chooses Tegile storage solution
A storage solution that addresses company growth and performance for business-critical applications of caseware archive and search along with other key operational systems.
Security and trust: The backbone of doing business over the internet
Explores the current state of website security and the contributions Symantec is making to help organizations protect critical data and build trust with customers.
Reg Reader Research: SaaS based Email and Office Productivity Tools
Read this Reg reader report which provides advice and guidance for SMBs towards the use of SaaS based email and Office productivity tools.
Security for virtualized datacentres
Legacy security solutions are inefficient due to the architectural differences between physical and virtual environments.