Feeds

Canadian kid uses supercomputing to cure cystic fibrosis

16-year-old cops prize for developing drug cocktail

  • alert
  • submit to reddit

Secure remote control for conventional and virtual desktops

A Canadian teenager has scooped a CAN$5,000 prize and deserved glory after successfully wielding the power of a scientific supercomputing network to develop a mix of drugs which could be used to fight cystic fibrosis.

Marshall Zhang, a Grade 11 student at Bayview Secondary School in Richmond Hill near Toronto, used Canada's collaborative SCINET super-net to model the effects of different compounds on the mutant proteins responsible for cystic fibrosis. The debilitating disease causes the natural protective mucus lining sufferers' lungs to become thick and sticky, forming an inviting environment for potentially fatal infections.

"Marshall's findings show that computational methods can drive the discovery of compounds that may offer effective treatment for cystic fibrosis," comments Dr Christine Bear of Canada's Hospital for Sick Children. Zhang carried out his groundbreaking work in Bear's lab.

Apparently the young scientist suspected that combining two drugs could work more effectively than using one alone. He first modelled the effects of his plan in silico, then proved it using living cells in culture.

"The cells treated with the two drugs were functioning as if they were the cells of healthy individuals," says Zhang. "The thrill of knowing that I was on the forefront of current knowledge was absolutely the best thing about my experience ... getting a taste of real research has definitely driven me towards pursuing science in the future."

The new drug treatment impressed the judges in the 2011 Sanofi-Aventis BioTalent Challenge, leading them to award Zhang first prize on Monday. it should be borne in mind that his new treatment, should it pass through development and testing successfully, would take years to become available.

Other winners in the compo included a trio of youths who developed a way of making vegetarian sorbet. There's more for those interested here. ®

Intelligent flash storage arrays

More from The Register

next story
FORGET the CLIMATE: FATTIES are a MUCH BIGGER problem - study
Fat guy? Drink or smoke? You're worse than a TERRORIST
Renewable energy 'simply WON'T WORK': Top Google engineers
Windmills, solar, tidal - all a 'false hope', say Stanford PhDs
Rosetta probot drilling DENIED: Philae has its 'LEG in the AIR'
NOT best position for scientific fulfillment
SEX BEAST SEALS may be egging each other on to ATTACK PENGUINS
Boffin: 'I think the behaviour is increasing in frequency'
HUMAN DNA 'will be FOUND ON MOON' – rocking boffin Brian Cox
Crowdfund plan to stimulate Blighty's space programme
Post-pub nosh neckfiller: The MIGHTY Scotch egg
Off to the boozer? This delicacy might help mitigate the effects
I'M SO SORRY, sobs Rosetta Brit boffin in 'sexist' sexy shirt storm
'He is just being himself' says proud mum of larger-than-life physicist
NASA launches new climate model at SC14
75 days of supercomputing later ...
LIFE, JIM? Comet probot lander found 'ORGANICS' on far-off iceball
That's it for God, then – if Comet 67P has got complex molecules
prev story

Whitepapers

Choosing cloud Backup services
Demystify how you can address your data protection needs in your small- to medium-sized business and select the best online backup service to meet your needs.
A strategic approach to identity relationship management
ForgeRock commissioned Forrester to evaluate companies’ IAM practices and requirements when it comes to customer-facing scenarios versus employee-facing ones.
High Performance for All
While HPC is not new, it has traditionally been seen as a specialist area – is it now geared up to meet more mainstream requirements?
Getting ahead of the compliance curve
Learn about new services that make it easy to discover and manage certificates across the enterprise and how to get ahead of the compliance curve.
Saudi Petroleum chooses Tegile storage solution
A storage solution that addresses company growth and performance for business-critical applications of caseware archive and search along with other key operational systems.