Feeds

Canadian kid uses supercomputing to cure cystic fibrosis

16-year-old cops prize for developing drug cocktail

  • alert
  • submit to reddit

Intelligent flash storage arrays

A Canadian teenager has scooped a CAN$5,000 prize and deserved glory after successfully wielding the power of a scientific supercomputing network to develop a mix of drugs which could be used to fight cystic fibrosis.

Marshall Zhang, a Grade 11 student at Bayview Secondary School in Richmond Hill near Toronto, used Canada's collaborative SCINET super-net to model the effects of different compounds on the mutant proteins responsible for cystic fibrosis. The debilitating disease causes the natural protective mucus lining sufferers' lungs to become thick and sticky, forming an inviting environment for potentially fatal infections.

"Marshall's findings show that computational methods can drive the discovery of compounds that may offer effective treatment for cystic fibrosis," comments Dr Christine Bear of Canada's Hospital for Sick Children. Zhang carried out his groundbreaking work in Bear's lab.

Apparently the young scientist suspected that combining two drugs could work more effectively than using one alone. He first modelled the effects of his plan in silico, then proved it using living cells in culture.

"The cells treated with the two drugs were functioning as if they were the cells of healthy individuals," says Zhang. "The thrill of knowing that I was on the forefront of current knowledge was absolutely the best thing about my experience ... getting a taste of real research has definitely driven me towards pursuing science in the future."

The new drug treatment impressed the judges in the 2011 Sanofi-Aventis BioTalent Challenge, leading them to award Zhang first prize on Monday. it should be borne in mind that his new treatment, should it pass through development and testing successfully, would take years to become available.

Other winners in the compo included a trio of youths who developed a way of making vegetarian sorbet. There's more for those interested here. ®

Providing a secure and efficient Helpdesk

More from The Register

next story
SECRET U.S. 'SPACE WARPLANE' set to return from SPY MISSION
Robot minishuttle X-37B returns after almost 2 years in orbit
LOHAN crash lands on CNN
Overflies Die Welt en route to lively US news vid
You can crunch it all you like, but the answer is NOT always in the data
Hear that, 'data journalists'? Our analytics prof holds forth
Experts brand LOHAN's squeaky-clean box
Phytosanitary treatment renders Vulture 2 crate fit for export
No sail: NASA spikes Sunjammer
'Solar sail' demonstrator project binned
Carry On Cosmonaut: Willful Child is a poor taste Star Trek parody
Cringeworthy, crude and crass jokes abound in Steven Erikson’s sci-fi debut
Origins of SEXUAL INTERCOURSE fished out of SCOTTISH LAKE
Fossil find proves it first happened 385 million years ago
Human spacecraft dodge COMET CHUNKS pelting off Mars
Odyssey orbiter yet to report, though - comet's trailing trash poses new threat
prev story

Whitepapers

Forging a new future with identity relationship management
Learn about ForgeRock's next generation IRM platform and how it is designed to empower CEOS's and enterprises to engage with consumers.
Cloud and hybrid-cloud data protection for VMware
Learn how quick and easy it is to configure backups and perform restores for VMware environments.
Three 1TB solid state scorchers up for grabs
Big SSDs can be expensive but think big and think free because you could be the lucky winner of one of three 1TB Samsung SSD 840 EVO drives that we’re giving away worth over £300 apiece.
Reg Reader Research: SaaS based Email and Office Productivity Tools
Read this Reg reader report which provides advice and guidance for SMBs towards the use of SaaS based email and Office productivity tools.
Security for virtualized datacentres
Legacy security solutions are inefficient due to the architectural differences between physical and virtual environments.