Feeds

Canadian kid uses supercomputing to cure cystic fibrosis

16-year-old cops prize for developing drug cocktail

  • alert
  • submit to reddit

Application security programs and practises

A Canadian teenager has scooped a CAN$5,000 prize and deserved glory after successfully wielding the power of a scientific supercomputing network to develop a mix of drugs which could be used to fight cystic fibrosis.

Marshall Zhang, a Grade 11 student at Bayview Secondary School in Richmond Hill near Toronto, used Canada's collaborative SCINET super-net to model the effects of different compounds on the mutant proteins responsible for cystic fibrosis. The debilitating disease causes the natural protective mucus lining sufferers' lungs to become thick and sticky, forming an inviting environment for potentially fatal infections.

"Marshall's findings show that computational methods can drive the discovery of compounds that may offer effective treatment for cystic fibrosis," comments Dr Christine Bear of Canada's Hospital for Sick Children. Zhang carried out his groundbreaking work in Bear's lab.

Apparently the young scientist suspected that combining two drugs could work more effectively than using one alone. He first modelled the effects of his plan in silico, then proved it using living cells in culture.

"The cells treated with the two drugs were functioning as if they were the cells of healthy individuals," says Zhang. "The thrill of knowing that I was on the forefront of current knowledge was absolutely the best thing about my experience ... getting a taste of real research has definitely driven me towards pursuing science in the future."

The new drug treatment impressed the judges in the 2011 Sanofi-Aventis BioTalent Challenge, leading them to award Zhang first prize on Monday. it should be borne in mind that his new treatment, should it pass through development and testing successfully, would take years to become available.

Other winners in the compo included a trio of youths who developed a way of making vegetarian sorbet. There's more for those interested here. ®

Build a business case: developing custom apps

More from The Register

next story
Asteroid's DINO KILLING SPREE just bad luck – boffins
Sauricide WASN'T inevitable, reckon scientists
BEST BATTERY EVER: All lithium, all the time, plus a dash of carbon nano-stuff
We have found the Holy Grail (of batteries) - boffins
The Sun took a day off last week and made NO sunspots
Someone needs to get that lazy star cooking again before things get cold around here
Boffins discuss AI space program at hush-hush IARPA confab
IBM, MIT, plenty of others invited to fill Uncle Sam's spy toolchest, but where's Google?
Famous 'Dish' radio telescope to be emptied in budget crisis: CSIRO
Radio astronomy suffering to protect Square Kilometre Array
Bad back? Show some spine and stop popping paracetamol
Study finds common pain-killer doesn't reduce pain or shorten recovery
Forty-five years ago: FOOTPRINTS FOUND ON MOON
NASA won't be back any time soon, sadly
prev story

Whitepapers

Implementing global e-invoicing with guaranteed legal certainty
Explaining the role local tax compliance plays in successful supply chain management and e-business and how leading global brands are addressing this.
Consolidation: The Foundation for IT Business Transformation
In this whitepaper learn how effective consolidation of IT and business resources can enable multiple, meaningful business benefits.
Application security programs and practises
Follow a few strategies and your organization can gain the full benefits of open source and the cloud without compromising the security of your applications.
How modern custom applications can spur business growth
Learn how to create, deploy and manage custom applications without consuming or expanding the need for scarce, expensive IT resources.
Securing Web Applications Made Simple and Scalable
Learn how automated security testing can provide a simple and scalable way to protect your web applications.