Feeds

Brit scientists brew up three-parent embryo

Two mums and one dad fight hereditary diseases

Top three mobile application threats

British scientists have successfully created "three parent" embryos using a technique they hope will offer "effective treatments for a range of serious hereditary diseases within five years".

The research could benefit mothers who suffer from mitochondrial DNA defects which might be inherited by their offspring and provoke any one of 40 different diseases, including those causing "fatal liver, heart and brain disorders, deafness, muscular problems and forms of epilepsy", as Reuters explains.

The Newcastle University team manipulated three DNA sources - the parents' nuclear DNA taken from a fertilised egg created by IVF, and an egg from a third party from which the nucleus had been removed. They transplanted the nuclear DNA into the nucleus-free host egg, thereby creating a foetus with its parents' genes inherited from the nuclear DNA but with the mitochondrial DNA of the second "mum".

Team member Patrick Chinnery summarised to Reuters: "The idea is simply to swap the bad diseased mitochondria - give a transplant, if you like - for good healthy ones from a donor. We're trying to prevent kids being born with fatal diseases."

The team experimented on "abnormal embryos left over from IVF therapy" to create the two-mum-one-dad embryos, which were "destroyed after six days".

Reuters concludes: "Stiff opposition to the technique is likely from critics of embryo research who fear the creation of designer babies." ®

Bootnote

Mitochondrial DNA is inherited exclusively from the mother. Sperm do carry mitochondrial DNA, but this is "destroyed" within the embryo after fertilisation.

3 Big data security analytics techniques

More from The Register

next story
KILLER SPONGES menacing California coastline
Surfers are safe, crustaceans less so
Opportunity selfie: Martian winds have given the spunky ol' rover a spring cleaning
Power levels up 70 per cent as the rover keeps on truckin'
Liftoff! SpaceX Falcon 9 lifts Dragon on third resupply mission to ISS
SpaceX snaps smartly into one-second launch window
KILLER ROBOTS, DNA TAMPERING and PEEPING CYBORGS: the future looks bright!
Americans optimistic about technology despite being afraid of EVERYTHING
Discovery time for 200m WONDER MATERIALS shaved from 4 MILLENNIA... to 4 years
Alloy, Alloy: Boffins in speed-classification breakthrough
R.I.P. LADEE: Probe smashes into lunar surface at 3,600mph
Swan dive signs off successful science mission
Elon Musk's LEAKY THRUSTER gas stalls Space Station supply run
Helium seeps from Falcon 9 first stage, delays new legs for NASA robonaut
prev story

Whitepapers

Securing web applications made simple and scalable
In this whitepaper learn how automated security testing can provide a simple and scalable way to protect your web applications.
3 Big data security analytics techniques
Applying these Big Data security analytics techniques can help you make your business safer by detecting attacks early, before significant damage is done.
The benefits of software based PBX
Why you should break free from your proprietary PBX and how to leverage your existing server hardware.
Top three mobile application threats
Learn about three of the top mobile application security threats facing businesses today and recommendations on how to mitigate the risk.
Combat fraud and increase customer satisfaction
Based on their experience using HP ArcSight Enterprise Security Manager for IT security operations, Finansbank moved to HP ArcSight ESM for fraud management.