Feeds

Oz organ recipient changes blood group

A 'one-in-six-billion miracle'

Securing Web Applications Made Simple and Scalable

An Australian teenager has been dubbed a "one-in-six-billion miracle" after her blood group changed following a liver transplant, Reuters reports.

Demi-Lee Brennan, now 15, suffered liver failure at nine and received a donated replacement. She subsequently became ill while on anti-rejection drugs, but her blood group inexplicably switched from O negative to O postive, while her new organ's blood stem cells "invaded" her bone marrow and took control of her entire immune system.

Doctors quickly took her off the anti-rejection drugs, "realising her blood type - and immune system - had taken on the characteristics of her organ donor", as Oz's Daily Telegraph puts it.

Mystified doctors from Sydney's Westmead Childrens' Hospital admitted they had "no explanation" for the teen's recovery. Pediatric hepatologist Michael Stormon said: "There was no precedent for this having happened at any other time, so we were sort of flying by the seat of our pants."

The hospital's former transplant unit head, Stuart Dorney, said Brennan's treatment could prove significant for organ transplant treatment, because "normally the immune system of recipients attacked the transplanted tissue".

He concluded: "We now need to go back over everything that happened to Demi-Lee and see why, and if it can be replicated. We think because we used a young person's liver and Demi-Lee had low white blood cells, that could have been a reason."

Ms Brennan, meanwhile, is understandably delighted with her one-in-six-billion transformation, which is reported in the latest issue of The New England Journal of Medicine. She told local media: "It's like my second chance at life. It's kind of hard to believe." ®

HP ProLiant Gen8: Integrated lifecycle automation

More from The Register

next story
Malaysian Airlines flight MH17 claimed lives of HIV/AIDS cure scientists
Researchers, advocates, health workers among those on shot-down plane
The Sun took a day off last week and made NO sunspots
Someone needs to get that lazy star cooking again before things get cold around here
Mwa-ha-ha-ha! Eccentric billionaire Musk gets his PRIVATE SPACEPORT
In the Lone Star State, perhaps appropriately enough
MARS NEEDS OCEANS to support life - and so do exoplanets
Just being in the Goldilocks zone doesn't mean there'll be anyone to eat the porridge
Diary note: Pluto's close-up is a year from … now!
New Horizons is less than a year from the dwarf planet
Forty-five years ago: FOOTPRINTS FOUND ON MOON
NASA won't be back any time soon, sadly
prev story

Whitepapers

Top three mobile application threats
Prevent sensitive data leakage over insecure channels or stolen mobile devices.
The Essential Guide to IT Transformation
ServiceNow discusses three IT transformations that can help CIO's automate IT services to transform IT and the enterprise.
Mobile application security vulnerability report
The alarming realities regarding the sheer number of applications vulnerable to attack, and the most common and easily addressable vulnerability errors.
How modern custom applications can spur business growth
Learn how to create, deploy and manage custom applications without consuming or expanding the need for scarce, expensive IT resources.
Consolidation: the foundation for IT and business transformation
In this whitepaper learn how effective consolidation of IT and business resources can enable multiple, meaningful business benefits.