Feeds

Japanese cook up cancer-busting synthicurry

Promising results from curcumin 'analogues'

The smart choice: opportunity from uncertainty

Japanese scientists have cooked up two synthetic versions of curcumin - the component of turmeric reputed to bring beneficial effects to those who like a quick Ruby.

As we previously reported, curcumin (the principal curcuminoid - a polyphenolic compound - in turmeric) may help to prevent the formation of tumours and combat Alzheimer's disease.

However, as Reuters notes, the compound "loses its anti-cancer attributes quickly when ingested". Accordingly, the latest edition of Molecular Cancer Therapeutics carries a report that boffins have "synthesized two variations - GO-Y030 and GO-Y031 - which have proved more potent and lasting than natural curcumin".

To prove the point, the scientists tested these "analogues" on mice with colorectal cancer. Hiroyuki Shibata, associate professor at Tohoku University's Institute of Development, Ageing and Cancer, duly reported: "Our new analogues (synthetic versions) have enhanced growth suppressive abilities against colorectal cancer cell lines, up to 30 times greater than natural curcumin.

"In a mouse model for colorectal cancer, mice fed with five milligrams of GO-Y030 or GO-Y031 fared 42 and 51 percent better, respectively, than did mice in the control group."

The scientists added that their concoctions may be able to fight other cancers, such as those of the stomach, breast, pancreas and lung. ®

The Power of One Infographic

More from The Register

next story
World Solar Challenge contender claims new speed record
One charge sees Sunswift travel 500kms at over 100 km/h
SMELL YOU LATER, LOSERS – Dumbo tells rats, dogs... humans
Junk in the trunk? That's what people have
The Sun took a day off last week and made NO sunspots
Someone needs to get that lazy star cooking again before things get cold around here
Boffins discuss AI space program at hush-hush IARPA confab
IBM, MIT, plenty of others invited to fill Uncle Sam's spy toolchest, but where's Google?
Bad back? Show some spine and stop popping paracetamol
Study finds common pain-killer doesn't reduce pain or shorten recovery
Forty-five years ago: FOOTPRINTS FOUND ON MOON
NASA won't be back any time soon, sadly
Jurassic squawk: Dinos were Earth's early FEATHERED friends
Boffins research: Ancient dinos may all have had 'potential' fluff
prev story

Whitepapers

Top three mobile application threats
Prevent sensitive data leakage over insecure channels or stolen mobile devices.
Implementing global e-invoicing with guaranteed legal certainty
Explaining the role local tax compliance plays in successful supply chain management and e-business and how leading global brands are addressing this.
Boost IT visibility and business value
How building a great service catalog relieves pressure points and demonstrates the value of IT service management.
Designing a Defense for Mobile Applications
Learn about the various considerations for defending mobile applications - from the application architecture itself to the myriad testing technologies.
Build a business case: developing custom apps
Learn how to maximize the value of custom applications by accelerating and simplifying their development.