Feeds

Japanese cook up cancer-busting synthicurry

Promising results from curcumin 'analogues'

Application security programs and practises

Japanese scientists have cooked up two synthetic versions of curcumin - the component of turmeric reputed to bring beneficial effects to those who like a quick Ruby.

As we previously reported, curcumin (the principal curcuminoid - a polyphenolic compound - in turmeric) may help to prevent the formation of tumours and combat Alzheimer's disease.

However, as Reuters notes, the compound "loses its anti-cancer attributes quickly when ingested". Accordingly, the latest edition of Molecular Cancer Therapeutics carries a report that boffins have "synthesized two variations - GO-Y030 and GO-Y031 - which have proved more potent and lasting than natural curcumin".

To prove the point, the scientists tested these "analogues" on mice with colorectal cancer. Hiroyuki Shibata, associate professor at Tohoku University's Institute of Development, Ageing and Cancer, duly reported: "Our new analogues (synthetic versions) have enhanced growth suppressive abilities against colorectal cancer cell lines, up to 30 times greater than natural curcumin.

"In a mouse model for colorectal cancer, mice fed with five milligrams of GO-Y030 or GO-Y031 fared 42 and 51 percent better, respectively, than did mice in the control group."

The scientists added that their concoctions may be able to fight other cancers, such as those of the stomach, breast, pancreas and lung. ®

Build a business case: developing custom apps

More from The Register

next story
Asteroid's DINO KILLING SPREE just bad luck – boffins
Sauricide WASN'T inevitable, reckon scientists
BEST BATTERY EVER: All lithium, all the time, plus a dash of carbon nano-stuff
We have found the Holy Grail (of batteries) - boffins
The Sun took a day off last week and made NO sunspots
Someone needs to get that lazy star cooking again before things get cold around here
Boffins discuss AI space program at hush-hush IARPA confab
IBM, MIT, plenty of others invited to fill Uncle Sam's spy toolchest, but where's Google?
Famous 'Dish' radio telescope to be emptied in budget crisis: CSIRO
Radio astronomy suffering to protect Square Kilometre Array
Bad back? Show some spine and stop popping paracetamol
Study finds common pain-killer doesn't reduce pain or shorten recovery
Forty-five years ago: FOOTPRINTS FOUND ON MOON
NASA won't be back any time soon, sadly
prev story

Whitepapers

Implementing global e-invoicing with guaranteed legal certainty
Explaining the role local tax compliance plays in successful supply chain management and e-business and how leading global brands are addressing this.
Consolidation: The Foundation for IT Business Transformation
In this whitepaper learn how effective consolidation of IT and business resources can enable multiple, meaningful business benefits.
Application security programs and practises
Follow a few strategies and your organization can gain the full benefits of open source and the cloud without compromising the security of your applications.
How modern custom applications can spur business growth
Learn how to create, deploy and manage custom applications without consuming or expanding the need for scarce, expensive IT resources.
Securing Web Applications Made Simple and Scalable
Learn how automated security testing can provide a simple and scalable way to protect your web applications.