The Register® — Biting the hand that feeds IT

Feeds

Geneticists report 'semi-identical' twins

Egg and sperm three-way

SaaS data loss: The problem you didn’t know you had

Geneticists in the US have discovered a previously unknown kind of twins they have called semi-identical. The twins are identical on their mother's side, but only share half of their father's DNA.

The discovery, which has been published in the journal Nature, has prompted some to suggest that the current classification system for twins is too simple and needs to be revisited.

The twins are technically chimeras: that is, their cells are not genetically uniform. Some cells contain male cells with an X and Y chromosome, others have female cells bearing a double load of Xs. In the journal Human Genetics, the researchers report that the proportion of XY and XX cells varies depending on the kind of tissue being examined.

For the genes to be distributed in this way, two sperm cells must have fertilised a single egg. Some DNA from each sperm is present in each child.

The sequence of events needed for the children to have been born is extremely unlikely: some scientists suggest the pair may be unique.

First, two sperm must fertilise a single egg. This does happen in about one percent of human conceptions. More often than not the fertilised egg does not form a viable embryo. This embryo must then split to form twins, who if they are to be identified as semi-identical, must subsequently come to the attention of scientists.

In this case, one of the twins was born with "ambiguous" genitalia, which brought in the scientists. They discovered that the baby is a true hermaphrodite, with both testicular and ovarian tissue, while the other twin is anatomically male.

Both children, now toddlers, are reportedly growing normally and have no mental developmental abnormalities.

According to Nature.com, in 2003 biologist Michael Golubovsky predicted that this kind of intermediate twin could result from "double fertilisation". He told the news service: There are a lot of unclear situations in the genetics of twins and twinning. We need to keep our eyes open for other unusual scenarios." ®

Magic Quadrant for Enterprise Backup/Recovery

Latest Comments

Coming soon...

Coming soon...the 'Semi-Genius'

0
0

More from The Register

 breaking news
You've seen the Large Hadron Collider. Now comes the HUGE Hadron Collider
International Linear Collider ready to rock and roll
Headbangers have a gas, gas, gas in mosh pits
Boffins say heavy metal crowds behave like The Vapours
Hubble spies unlikely planet being born in hostile neighborhood
Hoovering a cloud of sand 7.5 billion miles from a tiny star
 breaking news
Jaguar to open new car-making factory in Blighty (virtually)
Britain still makes stuff, it's just not real any more...
 breaking news
China's second woman 'naut blasts off for coupling in HEAVEN
Wang and pals test the cosmic waters for Chinese space station
Scientists investigate 'dark lightning' threat to aircraft passengers
One stormy flight could give lifetime radiation dose
 breaking news
Chinese 'nauts prep for next coupling in Heaven, clear way for new station
Second woman taikonaut and pals test tech for China's own orbiting platform
Boffins hide cute kitty behind invisibility shield
No polarisation or microwaves needed, yet the cat and fish disappear
 breaking news