Feeds

Boffins decode Chromosome 16

Fulfil USA's Human Genome commitment

  • alert
  • submit to reddit

A new approach to endpoint data protection

Scientists at the US Department of Energy Joint Genome Institute (JGI) have finished analysing and sequencing Chromosome 16. This completes the US share of the Human Genome Project, JGI said yesterday.

The research, published in today's issue of the science journal Nature, analysed the 880 genes, together consisting of 78m bases, making up Chromosome 16. These genes are implicated in the development of breast and prostate cancer, adult polycystic kidney disease, and Crohn's disease.

The scientists found many points where segmented duplication had occurred - sections of the chromosome were duplicated at other points on the chromosome, and even on entirely different chromosomes. They compared these regions to sequences in the genomes of other vertebrates, including chickens, dogs, mice and chimpanzees, looking for changes to the sequence since the last common ancestor, ranging from 5m to 400m years ago.

Work on Chromosome 16 at the DoE began in 1988 as part of DNA repair-gene studies. It was discovered that some of the genes on the chromosome were implicated in the detoxification and transport of heavy metals.

JGI is the first of the five primary Human Genome Project sequencing sites to publish a scientific article detailing the sequences of the chromosomes under their jurisdiction.

The JGI is now focusing its resources on other projects: "The considerable resources that the DoE has assembled to tackle the human genome are now being dedicated to illuminating the genomes of organisms that may figure into biological solutions to such challenges as economical hydrogen production, carbon sequestration, and environmental clean-up," said US Senator Pete Domenici, a Congressional proponent of efforts to sequence the human genome. ®

Related stories

£147.5m boost for British particle accelerators
Human genome data in hacker peril shocker
Human Genome out on CD

The Essential Guide to IT Transformation

More from The Register

next story
Just TWO climate committee MPs contradict IPCC: The two with SCIENCE degrees
'Greenhouse effect is real, but as for the rest of it ...'
Asteroid's DINO KILLING SPREE just bad luck – boffins
Sauricide WASN'T inevitable, reckon scientists
Brit amateur payload set to complete full circle around PLANET EARTH
Ultralight solar radio tracker in glorious 25,000km almost-space odyssey
Boffins spot weirder quantum capers as neutrons take the high road, spin takes the low
Cheshire cat effect see neutrons and their properties walk different paths
NASA Mars rover FINALLY equals 1973 Soviet benchmark
Yet to surpass ancient Greek one, however
Famous 'Dish' radio telescope to be emptied in budget crisis: CSIRO
Radio astronomy suffering to protect Square Kilometre Array
prev story

Whitepapers

7 Elements of Radically Simple OS Migration
Avoid the typical headaches of OS migration during your next project by learning about 7 elements of radically simple OS migration.
Implementing global e-invoicing with guaranteed legal certainty
Explaining the role local tax compliance plays in successful supply chain management and e-business and how leading global brands are addressing this.
Consolidation: The Foundation for IT Business Transformation
In this whitepaper learn how effective consolidation of IT and business resources can enable multiple, meaningful business benefits.
Solving today's distributed Big Data backup challenges
Enable IT efficiency and allow a firm to access and reuse corporate information for competitive advantage, ultimately changing business outcomes.
A new approach to endpoint data protection
What is the best way to ensure comprehensive visibility, management, and control of information on both company-owned and employee-owned devices?