Feeds

Boffins grow breasts on mice

We're not even going to go there - this is cancer research

  • alert
  • submit to reddit

Top three mobile application threats

Researchers have managed to grow human breast tissue on mice as part of an investigation into how breast cancer develops in humans.

Genetically-modified mice are often used in cancer research, but breast cancer works differently in mice than in humans. The hope is that by studying the transplanted tissue, researchers will get an insight into the early stages of the disease.

First reported in the medical journal Proceedings of the National Academy of Sciences, this particular research sounds very plausible.

Previous attempts to grow human breasts on mice have only used epithelial cells. According to Nature these cells line the milk ducts, and are where breast cancers start. In this experiment, two types of cell are transplanted: the epithelial cells and fibroblasts, or support cells.

The fibroblasts are blasted with X-Rays before being transplanted. The research team. led by Weinberg of the Whitehead Institute for Biomedical Research in Boston, used cells from women who had had breast reduction surgery. Weinberg thinks the irradiated fibroblasts help the epithelial cells to survive, but isn’t quite sure how.

If the fibroblasts were made to produce a protein present in tumours, the epithelial cells became cancerous. This, the researchers say, suggests that latent mutations emerge, or are switched on by the protein. ®

3 Big data security analytics techniques

More from The Register

next story
Fancy joining Reg hack on quid-a-day challenge?
Recruiting now for charity starvation diet
Red-faced LOHAN team 'fesses up in blown SPEARS fuse fiasco
Standing in the corner, big pointy 'D' hats
KILLER SPONGES menacing California coastline
Surfers are safe, crustaceans less so
Opportunity selfie: Martian winds have given the spunky ol' rover a spring cleaning
Power levels up 70 per cent as the rover keeps on truckin'
KILLER ROBOTS, DNA TAMPERING and PEEPING CYBORGS: the future looks bright!
Americans optimistic about technology despite being afraid of EVERYTHING
Discovery time for 200m WONDER MATERIALS shaved from 4 MILLENNIA... to 4 years
Alloy, Alloy: Boffins in speed-classification breakthrough
Elon Musk's LEAKY THRUSTER gas stalls Space Station supply run
Helium seeps from Falcon 9 first stage, delays new legs for NASA robonaut
prev story

Whitepapers

Securing web applications made simple and scalable
In this whitepaper learn how automated security testing can provide a simple and scalable way to protect your web applications.
3 Big data security analytics techniques
Applying these Big Data security analytics techniques can help you make your business safer by detecting attacks early, before significant damage is done.
The benefits of software based PBX
Why you should break free from your proprietary PBX and how to leverage your existing server hardware.
Top three mobile application threats
Learn about three of the top mobile application security threats facing businesses today and recommendations on how to mitigate the risk.
Combat fraud and increase customer satisfaction
Based on their experience using HP ArcSight Enterprise Security Manager for IT security operations, Finansbank moved to HP ArcSight ESM for fraud management.