Feeds

Boffins grow breasts on mice

We're not even going to go there - this is cancer research

  • alert
  • submit to reddit

Next gen security for virtualised datacentres

Researchers have managed to grow human breast tissue on mice as part of an investigation into how breast cancer develops in humans.

Genetically-modified mice are often used in cancer research, but breast cancer works differently in mice than in humans. The hope is that by studying the transplanted tissue, researchers will get an insight into the early stages of the disease.

First reported in the medical journal Proceedings of the National Academy of Sciences, this particular research sounds very plausible.

Previous attempts to grow human breasts on mice have only used epithelial cells. According to Nature these cells line the milk ducts, and are where breast cancers start. In this experiment, two types of cell are transplanted: the epithelial cells and fibroblasts, or support cells.

The fibroblasts are blasted with X-Rays before being transplanted. The research team. led by Weinberg of the Whitehead Institute for Biomedical Research in Boston, used cells from women who had had breast reduction surgery. Weinberg thinks the irradiated fibroblasts help the epithelial cells to survive, but isn’t quite sure how.

If the fibroblasts were made to produce a protein present in tumours, the epithelial cells became cancerous. This, the researchers say, suggests that latent mutations emerge, or are switched on by the protein. ®

Secure remote control for conventional and virtual desktops

More from The Register

next story
Our LOHAN spaceplane ballocket Kickstarter climbs through £8000
Through 25 per cent but more is needed: Get your UNIQUE rewards!
LOHAN tunes into ultra long range radio
And verily, Vultures shall speak status unto distant receivers
EOS, Lockheed to track space junk from Oz
WA facility gets laser-eyes out of the fog
Volcanic eruption in Iceland triggers CODE RED aviation warning
Lava-spitting Bárðarbunga prompts action from Met Office
NASA to reformat Opportunity rover's memory from 125 million miles away
Interplanetary admins will back up data and get to work
Major cyber attack hits Norwegian oil industry
Statoil, the gas giant behind the Scandie social miracle, targeted
prev story

Whitepapers

Endpoint data privacy in the cloud is easier than you think
Innovations in encryption and storage resolve issues of data privacy and key requirements for companies to look for in a solution.
Implementing global e-invoicing with guaranteed legal certainty
Explaining the role local tax compliance plays in successful supply chain management and e-business and how leading global brands are addressing this.
Advanced data protection for your virtualized environments
Find a natural fit for optimizing protection for the often resource-constrained data protection process found in virtual environments.
Boost IT visibility and business value
How building a great service catalog relieves pressure points and demonstrates the value of IT service management.
Next gen security for virtualised datacentres
Legacy security solutions are inefficient due to the architectural differences between physical and virtual environments.